Based on these results, the company intends to proceed with a confirmatory
in-vitro study with additional dilution levels to fully explore the
capabilities of the QR-435 compound. The new study will also be conducted by
Retroscreen Virology Ltd., and should the new study confirm the previous
results, animal model studies will be considered as a next step in the
development process.
Richard Rosenbloom, MD, Ph.D., Executive Vice President and Chief Operations
Officer of Quigley Pharma, stated, "Previous in-vitro and in-vivo studies have
suggested that QR-435 has broad anti-viral properties for applications such as
Influenza A&B , SARS, and Herpes Simplex 1. Therefore, in view of these current
findings, it is clear that this interesting formulation has therapeutic
potential and we intend to embark on the FDA regulatory path for approval."
Given the broad anti-viral properties of QR-435, the company intends to pursue
further development as a prescription medication, and thus will reconsider the
ongoing testing of its compound QR-334, a derivative compound, which was
intended as an over-the-counter medication. QR-334 is currently being evaluated
in clinical trials to relieve Sialorrhea, excess secretions of the salivary
glands.
Retroscreen Virology Limited is an independent research virology company
affiliated with the University of London. Professor John S. Oxford, the firm's
senior scientist, is Professor of Virology at St. Bartholomew's and The Royal
London School of Medicine and Dentistry at the University of London. Dr.
Oxford is the co-author of two standard texts on influenza and virology and has
published more than 250 scientific papers throughout the world. Retroscreen
specializes in developing anti-viral compounds and vaccines, and has worked
with many pharmaceutical companies to assist them in developing products that
now help to fight viral disease worldwide. Additional information is available
on the company's website at www.retroscreen.com.
The Quigley Corporation (Nasdaq: QGLY, http://www.Quigleyco.com) is a leading
developer and marketer of diversified health products including the Cold-Eeze®
family of patented zinc gluconate glycine (ZIGGTM) lozenges and sugar free
tablets. Cold-Eeze is the only (ZIGGTM) lozenge proven in two double-blind
studies to reduce the duration of the common cold from 7.6 to 4.4 days or by
42%. In addition to Over-The-Counter (OTC) products, the company has formed
Quigley Pharma Inc. (http://www.QuigleyPharma.com ), a wholly owned ethical
pharmaceutical subsidiary, to introduce a line of naturally-derived patented
prescription drugs. The Quigley Corporation's customers include leading
national wholesalers and distributors, as well as independent and chain food,
drug and mass merchandise stores and pharmacies. The Quigley Corporation makes
no representation that the U.S. Food and Drug Administration or any other
regulatory agency will grant an IND or take any other action to allow the
aforementioned products to be studied or marketed. Furthermore, no claim is
made that the potential medicine discussed here is safe, effective, or approved
by the Food and Drug Administration.
Certain statements in this press release are "forward-looking statements"
within the meaning of the Private Securities Litigation Reform Act of 1995 and
involve known and unknown risk, uncertainties and other factors that may cause
the company's actual performance or achievements to be materially different
from the results, performance or achievements expressed or implied by the
forward-looking statement. Factors that impact such forward-looking statements
include, among others, changes in worldwide general economic conditions,
changes in interest rates, government regulations, and worldwide competition.