DOYLESTOWN, PA, January 14, 2003 - The Quigley Corporation
(NASDAQ: QGLY), today announced that a Patent Application
previously assigned to The Quigley Corporation for an all-natural
compound was found effective in reducing the impact of influenza.
Quigley Pharma Inc., the Company's wholly owned ethical pharmaceutical
subsidiary, developed the formula.
The study was designed to test the efficacy of the Quigley
Pharma formula in a more advanced influenza model.
Retroscreen Virology Ltd, the research virology company affiliated
with the University of London, conducted the study. Professor
John S. Oxford, the firm's senior scientist, is Professor
of Virology at St. Bartholomew's and The Royal London School
of Medicine and Dentistry at the University of London. He
is the co-author of two standard texts on Influenza and Virology
and has published 250 scientific papers throughout the world.
The study report concluded that "the data indicated
that intranasal administration of the (Quigley Pharma) nasal
spray was effective in this model, with slightly differing
symptom resolutions."
In a previous statement, Professor Oxford said that an independent
audit of his previously conducted in-vitro study of the new
Quigley Pharma formulation had been confirmed to be effective
in killing three virulent strains of current Influenza 'A'
and 'B' viruses. At that time he recommended that additional
model studies be undertaken, which, if successful, he would
publish in a reputable medical journal.
These
additional studies have now been successfully completed, and
according to Professor Oxford, are encouraging. Professor
Oxford said "it is now important that further investigations
are considered to determine whether lower concentrations of
the test compounds will be as effective and that there is
a dose response. When we have sufficient data regarding toxicity,
a human study might be considered. That study would consist
of human influenza challenge testing."
Guy J. Quigley, President, Chairman and Chief Executive Officer
of The Quigley Corporation, stated: "At the conclusion
of the dosage response and toxicity testing, we will consider
the most appropriate strategy for the Company to pursue in
this process. We are continuing our ongoing research and development
efforts at Quigley Pharma. Under the direction of Dr. Richard
Rosenbloom, we hope to continue developing an exciting pipeline
of potential new all-natural medications to bring to the market."
Dr. Rosenbloom stated: "We are greatly encouraged by
the clinical and pre-clinical studies conducted on Quigley
Pharma formulations to date and the continuing progress toward
the approval process."
Influenza can cause localized epidemics and global pandemics
of acute respiratory infections. Although influenza is mostly
associated with a benign and self-limiting condition, there
is a significant link between mortality and infection of children,
elderly, and the persons with impaired immunity systems.
About
The Quigley Corporation
The Quigley
Corporation (NASDAQ: QGLY) is a leading developer and marketer
of diversified health products including the Cold-Eeze® family of patented zinc gluconate glycine (ZIGG(tm)) lozenges,
gums and sugar free tablets. Cold-Eeze is the only (ZIGG(tm))
lozenge proven in two double-blind studies to reduce the duration
of the common cold from 7.6 to 4.4 days or by 42%. In addition
to Over-The-Counter (OTC) products, the Company has formed
Quigley Pharma Inc. (www.QuigleyPharma.com), a wholly owned
ethical pharmaceutical subsidiary, to introduce a line of
patented prescription drugs. The Quigley Corporation's customers
include leading national wholesalers and distributors, as
well as independent and chain food, drug and mass merchandise
stores and pharmacies.
No claims are being made for the potential medicine discussed
in this press release to be safe, effective, or approved by
the Federal Food and Drug Administration (FDA).
Certain statements in this press release are "forward-looking
statements" within the meaning of the Private Securities
Litigation Reform Act of 1995 and involve known and unknown
risk, uncertainties and other factors that may cause the Company's
actual results, performance or achievements to be materially
different from the results, performance or achievements expressed
or implied by the forward-looking statement. Factors that
impact such forward-looking statements include, among others,
changes in worldwide general economic conditions, changes
in interest rates, government regulations, and worldwide competition.